Phenanthrenes and derivatives
Medchemexpress LLC Aristolochic acid C | 4849-90-5 | 327.25 | 5 MG
Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid acts as a phospholipase A2 (PLA2) inhibitor, which interferes with cortical microtubule arrays and root growth in Arabidopsis.
- Derivative of Aristolochic acid
- Acts as a phospholipase A2 (PLA2) inhibitor
- Disrupts cortical microtubule arrays
- Interferes with root growth in Arabidopsis
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | 99.3% | 524.5 g·mol⁻¹ | C22H27Cl2N7O2S | 200 MG
Dasatinib hydrochloride is a research-grade, ATP-competitive dual Src and Bcr-Abl kinase inhibitor supplied as the hydrochloride salt. It exhibits subnanomolar to low-nanomolar activity against its targets and is intended for laboratory and preclinical research applications; supplied at high purity for analytical use.
- High purity: 99.31%.
- Potent dual Src and Bcr-Abl inhibition at subnanomolar to low-nanomolar concentrations.
- Supplied as the hydrochloride salt in solid form for research use.
- Suitable for research and analytical applications; not for human consumption.
- Available in multiple pack sizes, including 200 MG.
TARGETMOL CHEMICALS INC Aristolochic acid B 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Aristolochic acid B (Aristolochic Acid II) is a natural product from the Aristolochaceae taxon and is one of the main components of aristolochic acid. Aristolochic acid is a mutagen and carcinogen, and Aristolochic acid B (Aristolochic Acid II) can show a greater carcinogenic risk in vivo than Aristolochic acid I. Purity 99.99%
Medchemexpress LLC Aristolochic acid Va | 108779-46-0 | 357.27 | 1 MG
Aristolochic acid Va is a natural compound isolated from *Aristolochia* plants. This high-purity compound is intended for research use only, supporting a wide range of studies in natural product chemistry and biological activity.
- Natural compound isolated from Aristolochia plants.
- Suitable for various research applications.
- High purity for reliable experimental results.
- Available in multiple sizes for research flexibility.
Cayman Chemical Aristolochic Acid, Purity: ≥98%, CAS: 313-67-7, 25 mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
eMolecules 58943-98-9 | Hexakis(2,2,3,3-tetrafluoropropoxy)phosphazene | Apollo Scientific US - Building Blocks | MFCD00798140 | 921.240 | C18H18F24N3O6P3 | 95.000 | FC(F)C(F)(F)COP1(OCC(F)(F)C(F)F)=NP(OCC(F)(F)C(F)F)(OCC(F)(F)C(F)F)=NP(OCC(F)(F)C(F)F)(OCC(F)(F)C(F)F)=N1 | 250mg | 398010245
Hexakis(2,2,3,3-tetrafluoropropoxy)phosphazene | Apollo Scientific US - Building Blocks | 58943-98-9 | MFCD00798140 | 921.240 | C18H18F24N3O6P3 | 95.000 | FC(F)C(F)(F)COP1(OCC(F)(F)C(F)F)=NP(OCC(F)(F)C(F)F)(OCC(F)(F)C(F)F)=NP(OCC(F)(F)C(F)F)(OCC(F)(F)C(F)F)=N1 | 250mg | 398010245
eMolecules 100077-38-1 | Triphenylene-2,3,6,7,10,11-hexathiol | ChemScene420.650 | C18H12S6 | 95.000 | Sc1cc2c(cc1S)c1cc(S)c(S)cc1c1cc(S)c(S)cc21 | 100mg | 632338653
Triphenylene-2,3,6,7,10,11-hexathiol | ChemScene | 100077-38-1420.650 | C18H12S6 | 95.000 | Sc1cc2c(cc1S)c1cc(S)c(S)cc1c1cc(S)c(S)cc21 | 100mg | 632338653
Medchemexpress LLC Nilotinib hydrochloride dihydrate | 00-00-0 | 99.9% | 602.01 g/mol | C28H27ClF3N7O3 | 200 MG
Nilotinib hydrochloride dihydrate is the dihydrate salt of nilotinib, a second-generation Bcr-Abl tyrosine kinase inhibitor used in oncology research. Supplied for research and analytical applications, it is intended for laboratory studies of chronic myelogenous leukemia mechanisms and kinase signaling. Not for human therapeutic use.
- Potent Bcr-Abl tyrosine kinase inhibitor.
- Suitable for in vitro and in vivo research models.
- High purity suitable for analytical applications (99.89%).
- Supplied as a solid with molecular weight 602.01 g/mol.
- Available in laboratory pack sizes for experimental use.
Sigma Aldrich Fine Chemicals Biosciences Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | 313-67-7 | MFCD00004996 |
Aristolochic acid I European Pharmacopoeia (EP) Reference Standard | Mol Wt: 341.27 | 313-67-7 | MFCD00004996 |
Medchemexpress LLC 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-, (3R,4S)-rel- | 1213777-80-0 | 723112 | 99.6% | C22H20O4 | 25 MG
Triphen diol is a phenol diol derivative known for its excellent anticancer activity against pancreatic cancer and cholangiocarcinoma. It induces pancreatic cell apoptosis through both caspase-mediated and caspase-independent mechanisms, and is intended for research use only.
- Inhibits proliferation of pancreatic cells (IC50 values: 8 μM for HPAC and PANC-1; 0.8 μM for MIAPaCa-2).
- Induces caspase-dependent apoptosis in MIAPaCa-2 and PANC-1 cells (60% early-stage, 30% late-stage).
- Reduces Bcl-2 levels in MIAPaCa-2 and HPAC cell lines.
- Significantly inhibits tumor proliferation in male Balb/c nude mice with MIAPaCa2 cells.
- Shows enhanced efficacy when combined with gemcitabine in vivo.